Anti- inflammatories and Heart Disease Side Effects 

A study published in PLOS Medicine recently suggests that the use of some non-steroidal anti inflammatory drugs (NSAIDs) may cause an elevated risk of cardiovascular disease:

Cardiovascular Risk with Non-Steroidal Anti-Inflammatory Drugs: Systematic Review of Population-Based Controlled Observational Studies

The article summary can be viewed here:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001098#abstract2

The study highlighted that the greatest risk occurred with the use of Diclofenac (eg Voltaren) and Celecoxib (eg Celebrex) NSAIDs. Voltaren, even at non-prescription dosages was linked to elevated cardiovascular risks.

Although Ibuprofen (Nurofen) at low doses was considered safe, it did produce an increased risk at higher dosages.